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Upon ligand binding, this presumably membrane-bound receptor transduces intracellular chemical/redox signals that relay messages for the regulation of gene expression, a phenomenon mainly involving the activation of transcription factors [2, 13, 14, 1618, 26, 34, 51, 70]

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Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symporters

Additionally, the lipoxygenase enzyme ALOX15 catalyzes the oxidation of PUFA-phosphatidylethanolamines (PUFA-PEs) into toxic lipid peroxides

Rather, it's involved in tissue repair